# What does Spyre Therapeutics (United States) use?

Spyre Therapeutics (United States) (spyre.com) shows public evidence of 18 tools, according to runsonwhat (last checked 2026-10-20).

- Industry: Biotechnology
- Size: 11–50 employees
- Based in: Waltham, United States
- Founded: 2013
- LinkedIn: https://www.linkedin.com/company/spyre-therapeutics

## Edge & Hosting

| Tool | Category | Evidence | Since |
|---|---|---|---|
| [Cloudflare](https://www.runsonwhat.com/reverse/cloudflare) | CDN & Edge | Website code |  |
| [GoDaddy](https://www.runsonwhat.com/reverse/godaddy) | DNS | DNS records |  |

## Application

| Tool | Category | Evidence | Since |
|---|---|---|---|
| [jQuery](https://www.runsonwhat.com/reverse/jquery) | Frontend | Website code |  |
| [Vimeo](https://www.runsonwhat.com/reverse/vimeo) | Media & UI | Website code |  |
| [Anthropic](https://www.runsonwhat.com/reverse/anthropic) | AI | DNS verification records |  |
| [OpenAI](https://www.runsonwhat.com/reverse/openai) | AI | DNS verification records |  |

## Go-to-market

| Tool | Category | Evidence | Since |
|---|---|---|---|
| [Webflow](https://www.runsonwhat.com/reverse/webflow) | Website & CMS | Custom domain, Website code |  |

## Company Ops

| Tool | Category | Evidence | Since |
|---|---|---|---|
| [Microsoft 365](https://www.runsonwhat.com/reverse/microsoft-365) | Workspace | Email records |  |
| [Apple Business](https://www.runsonwhat.com/reverse/apple) | Workspace | DNS verification records |  |
| [Let's Encrypt](https://www.runsonwhat.com/reverse/letsencrypt) | Security & Compliance | DNS records |  |
| [Proofpoint](https://www.runsonwhat.com/reverse/proofpoint) | Security & Compliance | Email records |  |
| [DigiCert](https://www.runsonwhat.com/reverse/digicert) | Security & Compliance | DNS records |  |
| [Google Trust Services](https://www.runsonwhat.com/reverse/google-trust) | Security & Compliance | DNS records |  |
| [EasyDMARC](https://www.runsonwhat.com/reverse/easydmarc) | Security & Compliance | Email records |  |
| [Smartsheet](https://www.runsonwhat.com/reverse/smartsheet) | Collaboration | DNS verification records |  |
| [Airtable](https://www.runsonwhat.com/reverse/airtable) | Collaboration | DNS verification records |  |
| [Rippling](https://www.runsonwhat.com/reverse/rippling) | People & HR | DNS verification records |  |

## FAQ

### What tools does Spyre Therapeutics (United States) use?

As of October 2026, runsonwhat has found 18 tools at Spyre Therapeutics (United States) (spyre.com) in public records. Edge & Hosting: Cloudflare and GoDaddy. Application: jQuery, Vimeo and Anthropic. Go-to-market: Webflow. Company Ops: Microsoft 365, Apple Business and Let's Encrypt. Last checked October 20, 2026.

### What email provider does Spyre Therapeutics (United States) use?

Spyre Therapeutics (United States) uses Microsoft 365 for email and office software, alongside Apple Business, according to runsonwhat (October 2026). runsonwhat found Microsoft 365 through email records that authorize Microsoft 365. Microsoft 365 is used by 711,315 companies runsonwhat tracks.

### What is Spyre Therapeutics (United States)'s website built with?

Spyre Therapeutics (United States) uses Webflow for its website, according to runsonwhat (October 2026). runsonwhat found Webflow through a subdomain that points at Webflow and code on spyre.com. Webflow is used by 34,914 companies runsonwhat tracks.

### What does Spyre Therapeutics (United States) use for hiring and HR?

Spyre Therapeutics (United States) uses Rippling for hiring and HR, according to runsonwhat (October 2026). runsonwhat found Rippling through a DNS verification record for Rippling. Rippling is used by 3,204 companies runsonwhat tracks.

### Does Spyre Therapeutics (United States) use jQuery?

Yes. runsonwhat found jQuery at Spyre Therapeutics (United States) through jQuery code on spyre.com. jQuery is a Frontend tool used by 916,796 companies runsonwhat tracks.

### Does Spyre Therapeutics (United States) use AI tools?

Yes. runsonwhat has found Anthropic and OpenAI at Spyre Therapeutics (United States); Anthropic, for example, through a DNS verification record for Anthropic. AI services called only from servers leave no public trace, so Spyre Therapeutics (United States) may use more AI tools than these.

### How does runsonwhat know what Spyre Therapeutics (United States) uses?

runsonwhat reads public records only. Of the 18 tools at Spyre Therapeutics (United States), 11 were found through DNS records, 3 through code on spyre.com, 3 through email records and 1 through subdomains that point at the vendor. A tool is listed only when a direct record backs it up; DNS is rechecked weekly and spyre.com about monthly.


---

Source: runsonwhat, https://www.runsonwhat.com/company/spyre.com (updated October 2026). Counts are companies with direct public evidence of the tool (DNS records, certificates, website code, a real-browser crawl, subprocessor lists), so they are lower bounds. Methodology: https://www.runsonwhat.com/methodology.